News

Mitophagy, a type of autophagy, removes damaged mitochondria to maintain cellular quality. It begins with the ULK1 kinase complex engaging receptors via FIP200. A recent study by SFB 1381 PIs Claudine Kraft, Laura Gámez-Díaz and Chris Meisinger, published in the Journal of Molecular Biology, demonstrates that phosphorylation of FIP200 regulates both early and late stages of mitophagy, emphasizing the importance of this signaling pathway.

Follow SFB 1381 on LinkedIn™: SFB 1381 – Protein Machineries.

SFB 1381 PI Nils Wiedemann (Project A07) was elected as a new member of the “Academia Europaea” in April 2024.

SFB 1381 PIs Sonja-Verena Albers (Project A01) and Oliver Einsle (Project A04) both received an Advanced Grant from the European Research Council (ERC).

The SFB 1381 retreat 2024 took place in Schluchsee on April 8/9 2024. Excellent talks, a fantastic poster session and lively discussions shaped this event, which was highly enjoyed by all participants and left everybody looking forward to the next stage of the project!

SFB 1381 PI Nora Vögtle with support of Friedel Drepper  and Oliver Einsle identified MiRA, a novel high molecular weight protein complex in the mitochondrial inner membrane and uncovered its molecular role to synchronize the assembly of the respiratory chain complexes and the ATP synthase thereby controlling OXPHOS stoichiometry. Publication in Developmental Cell.

Five doctoral students have been accepted into the Spemann Graduate School of Biology and Medicine (SGBM) SFB 1381 track.

Friedel Drepper and newly joint SFB 1381 PI Pitter Huesgen organised a successful SFB 1381 workshop on proteomics data analysis.

On the occasion of the international Women’s Day on March 8th, SFB 1381 PI Valérie Hilgers was interviewed regarding her experiences during her career path.

SFB 1381 PI Nora Vögtle (Project B04) was elected as a new member of the DFG review board (Fachkollegium).

SFB 3181 Associated PI Dr. Viviane Timmermann receives Marie Curie Postdoctoral Fellowship Award.

Recently associated SFB 1381 PI Viviane Timmermann (Project AI01: Mathematical Modelling of Cellular Protein Machineries) introduced her research in the frame of the SFB 1381 seminar series.

SFB 1381 workshop with hands-on training for PhD students, PostDocs (and PIs) involved in the CRC projects.

SFB 1381 PI Thorsten Hugel and his group shed light on the dynamics of the Hsp90 machinery. Publication in Nature Communications.

Fan Xu (project B9) defended his PhD thesis successfully.

Anuradha Bhattacharya (project B10) defended her PhD thesis successfully.

SFB 1381 PI Wolfgang Schamel and colleagues have engineered new forms of CAR-T cells to combat cancer. Publication in Nature Immunology.

A study by SFB 1381 PIs Asifa Akthar (B03) and Bettina Warscheid (B5), published in Nature Metabolism, showed that MOF is responsible for acetylation of mitochondrial proteins.